Publications

• 2024 Nov 6-10 SITC 2024 (poster 608)

  Final safety and efficacy update of SUPLEXA-101, a First-in-Human, Single-Agent Study of SUPLEXA Therapeutic Cells in Metastatic Solid Tumors

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• 2024 Nov 6-10 SITC 2024 (poster 378)

  Transcriptional and proteomic insights into the immunomodulatory nature of SUPLEXA cells: An autologous cellular therapy for cancers

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• 2023 Nov 1 -15 SITC 2023 (poster 727)

  Topline safety and efficacy update of SUPLEXA-101, a First-in-Human, Single Agent Study of SUPLEXA Therapeutic Cells in 28 Patients with Metastatic Solid Tumors

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• 2023 Nov 1 -15 SITC 2023 (poster 381)

  SUPLEXA, a multimodal autologous cellular therapy, shows immunomodulatory behavior in cancer patients consistent with improved anti-tumor immune function

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• 2023 April 25 Immuno-Oncology Insights 2023; 4(3), 89–104

  Alloplex Biotherapeutic’s SUPLEXA cells represent a new type of autologous adoptive cellular therapy for cancer

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• 2022 Nov 8 -12 SITC 2022 (poster 632)

  Clinical Update from a Phase 1, First-in-Human, Open-label Single Agent Study of SUPLEXA Therapeutic Cells in Patients with Metastatic Solid Tumors and Hematologic Malignancies

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• 2022 Oct 21-24 AACR Special Conference (poster B63)

  Exploratory immune phenotyping of longitudinal blood samples from the first-in-human phase 1 clinical trial of a novel autologous cellular therapy in patients with metastatic solid tumors

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• 2022 April 12 AACR Conference (poster 3599)

  Interleukin-10 and transforming growth factor-b do not suppress tumor killing activity of PBMC-derived SUPLEXA cells

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• 2021 November 15 SITC conference (poster 164)

  Potent Tumor Organoid Infiltration and Killing by PBMC Derived Effector Cells

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• 2019 Nov 6-10 Society for Immunotherapy of Cancer (SITC) conference

  Conversion of peripheral blood mononuclear cells into tumor-specific cytolytic cell populations using tumor cells engineered with multiple immunomodulatory factors

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• 2021 Mar 24-25 Innate Killer Cell conference

  A Differentiated and Broadly Applicable Autologous Whole Blood Derived Adoptive Cellular Therapy for Treating Cancer

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• 2021 Mar 26-29 ISCT conference (Poster 411)

  Characterization of a Novel Autologous Pan-Cancer Cellular Immunotherapy

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• 2021 April 9 AACR conference (poster 1531)

  Development of PBMC derived tumor effector cells with potent pan-cancer cytolytic activity for autologous cellular immunotherapy

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• 2021 April 9 AACR conference (Poster 1772)

  A novel approach for autologous pan-cancer cellular immunotherapy reveals dramatic expansion of αβ and γδ TCR T cell clonotypes indicative of an antigen-driven response

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• 2021 June 4-8 ASCO Conference (poster 7517)

  Engineered immunostimulatory cells can convert PBMCs from chronic lymphocytic leukemia (CLL) patients into potent tumor killing immune cells.

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• 2019 March 19 Nature.com Scientific Reports, volume 9, Article number: 4847

  Application of PMCA to screen for prion infection in a human cell line used to produce biological therapeutics.

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