On Friday 29 August, an independent Data Safety Monitoring Board ‘DSMB’ unanimously agreed that the trial of Alloplex Biotherapeutics Inc.’s SUPLEXA Therapeutic Cells should to continue to full enrollment.
Category: Backgrounder
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August 1, 2022
Independent Data Safety Monitoring Board agrees to continue enrollment in SUPLEXA first-in-human trial
No safety signals or adverse events were observed in the first cohort of three patients with solid cancer who have completed treatment with Alloplex Biotherapeutics Inc.'s SUPLEXA Therapeutic Cells.
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April 11, 2022
Alloplex SUPLEXA cells resist immunosuppressive action of two inhibitory cytokines typically found in tumor microenvironment
On April 12, 2022, Jim Lederer, MD, Chief Scientific Officer of Alloplex Biotherapeutics Inc. will present a Poster at the AACR 2022 Annual Meeting in New Orleans, Louisiana: AACR Abstract: IL-10/TGFβ Abstract Control Number: 3599 Title: Interleukin-10 and transforming growth factor-beta do not sup...
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January 17, 2022
Human Research Ethics Committee (HREC) in Australia approves the start of the first SUPLEXA Phase 1 Clinical Trial
Alloplex Biotherapeutics, Inc. (‘Alloplex’) – a private cellular therapeutics company dedicated to developing and commercializing a global first-in-class cellular therapeutic in oncology – today announced that the Human Research Ethics Committee (HREC) in Australia has approved the clinical...
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November 15, 2021
Alloplex presents poster describing novel tumor-killing cells at SITC 2021 Conference
Non-engineered SUPLEXA cells demonstrate potent activity against patient-derived cancer organoids in vitro.
Today Alloplex Biotherapeutics released details of its abstract entitled Potent Tumor Organoid Infiltration and Killing by PBMC-Derived Effector Cells presented at SITC 2021. Alloplex’s abstract shows that the organization can generate tumor-killing cells from PBMCs using a clinical grade manufact...